Diddy will host Alicia Keys' annual charity event that raises awareness about HIV and AIDS.
The piano-playing singer announced Tuesday that her husband, producer-rapper Swizz Beatz, will co-host the 11th annual Black Ball on Oct. 30 at New York City's Hammerstein Ballroom.
Keys, Nas, David Byrne and Angel Haze will perform.
Keep a Child Alive, Keys' charity launched in 2003, assists people affected by HIV and AIDS in Africa and India.
Last year's Black Ball raised $4 million and featured Carole King and Pharrell.